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Figure 2 | Respiratory Research

Figure 2

From: Therapeutic efficacy of TBC3711 in monocrotaline-induced pulmonary hypertension

Figure 2

Effect of TBC3711 on pulmonary artery acceleration time (ACT), cardiac output (CO), total pulmonary resistance (TPR) and oxygenation index (paO 2 /FiO 2 ) in monocrotaline (MCT)-induced pulmonary hypertension. Rats were treated with TBC3711 (30 mg/kg body weight/day, n = 14) or vehicle (n = 9) from day 21-35 after MCT-injection accompanied by echocardiography measurement and blood gas analysis. (a) Pulmonary artery acceleration time (ACT), (b) Cardiac output (CO), (c) Total pulmonary resistance (TPR) and (d) oxygenation index (paO2/FiO2) of different experimental groups are given. Bars represent mean ± SEM. One-way ANOVA with Newman-Keuls multiple comparison post-hoc test was performed for statistical analysis. *P < 0.05, ***P < 0.001.

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