In vivo imaging of the airway wall in asthma: fibered confocal fluorescence microscopy in relation to histology and lung function

Table 1 Subject characteristics of asthma (A) and healthy (H) subjects

	A	H
		Total	HA	HNA
Subjects (n)	8	8	5	3
Male/Female (n)	2/6	4/4	2/3	2/1
Age (years) ^a	24 (2)	28 (10)	30 (12)	23 (2)
FEV₁/FVC (%pred.)^a,*	96 (9)	108 (7)	105 (7)	113 (4)
Post-bronchodilator FEV ₁ (%pred.) ^a	108 (11)	115 (6)	115 (6)	114 (6)
Dose response slope (% decline FEV₁/μmol methacholine)^b,**	6.49 (3.47-31.30)	0.20 (0.04-0.30)	0.23 (0.10-0.49)	0.07 (0.03-0.23)

Total = all healthy control subjects; HA = healthy, atopic; HNA = healthy, non-atopic
^a Mean (SD)
^b Median (P25-P75)
* A vs. Total p = 0.012; A vs. HNA p = 0.016
** A vs. Total p = 0.001; A vs. HA p = 0.003; A vs. HNA p = 0.014

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