Figure 7From: Physiologic and molecular consequences of endothelial Bmpr2 mutationScatter plots indicating changes in illustrative genes from different gene ontology groups in Bmpr2delx4+ (black circles) or Bmpr2R899X (grey diamonds) PMVEC. In each plot, the y-axis indicates fold change compared to control PMVEC on a log2 scale. Points falling on the 1x line are thus identical to controls; those above are upregulated, and those below are downregulated. Error bars indicate standard deviation in replicates; if they are invisible, they are smaller than the symbol (experimental replicates were very similar). Bmpr2delx4+ and Bmpr2R899X PMVEC had very similar changes in apoptosis(A), proliferation (B), adhesion (C), and metabolic (D) genes, but divergent changes in inflammatory (E) and thrombotic (F) genes.Back to article page