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Figure 6 | Respiratory Research

Figure 6

From: Physiologic and molecular consequences of endothelial Bmpr2 mutation

Figure 6

Gene ontology classification of genes dysregulated in PMVEC cultured from BMPR2delx4+ mice (top) or Bmpr2R899X mice (bottom) indicates very similar patterns of gene dysregulation between mutation types. Angular width of sections corresponds to proportion of genes within that ontology group. Outer labels correspond to top-level gene ontology groups: inner circle corresponds to more detailed gene ontology classification, all from the biological process tree. Most genes fall into more than one lower-level category, and so lower-level categories selected are meant to be representative, but are somewhat arbitrary. Full GO listing is included in Supplemental Tables 1 and 2.

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