Diagnostic utility of C-reactive Protein combined with brain natriuretic peptide in acute pulmonary edema: a cross sectional study

Table 4 Performance characteristics of various cut off points of BNP or CRP, excluding mixed type edema

Cut-off points	Sensitivity	Specificity	PPV	NPV	Accuracy
BNP levels for CPE
≧400	80.3	66.0	76.0	71.4	74.2
≧500	69.0	83.1	84.5	66.7	75.0
≧600	60.6	84.9	84.3	61.6	71.0
CRP levels for ALI/ARDS
≧80	53.5	90.6	88.4	59.3	69.4
≧50	59.2	69.8	72.4	56.1	63.7
≧20	69.0	50.9	65.3	55.1	61.3

Cut-off points of BNP (pg/mL), CRP (mg/L), (%)
ALI: acute lung injury; ARDS: acute respiratory distress syndrome; BNP: brain natriuretic peptide; CRP: C-reactive protein; CPE: cardiogenic pulmonary edema; NPV: negative predictive value; PPV: positive predictive value

ISSN: 1465-993X