Diagnostic utility of C-reactive Protein combined with brain natriuretic peptide in acute pulmonary edema: a cross sectional study

Table 1 Criteria for the clinical diagnosis

No.	Clinical features	CPE	ALI/ARDS
1	PCWP in right heart catheterization (if examined), mmHg	> 18	≤ 18
2	Culture results and/or immunological test for infections	Negative	Positive
3	LVEF < 50% and/or diastolic dysfunction on echocardiography	Present	Absent
4	Pleural effusion on chest radiographs	Present	Absent
5	PaO₂ / FiO₂ > 400 within 3 days after diuresis	Present	Absent

CPE subjects were required No. 1 and No.2, together with at least two features in Nos. 3-5.
ALI/ARDS subjects were required No.1, together with at least three features in Nos. 2-5.
The patients who did not meet these diagnostic criteria were categorized as having mixed edema,
ALI: acute lung injury; ARDS: acute respiratory distress syndrome; CPE: cardiogenic pulmonary edema; LVEF: left ventricular ejection fraction; PCWP: pulmonary capillary wedge pressure

ISSN: 1465-993X