From: Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury
 | COPD patients | Smokers | Nonsmokers |
---|---|---|---|
 | (n= 14) | (n= 7) | (n= 8) |
Male/females, n | 12/2 | 7/0 | 2/6 |
Age, years | 65.9 ± 2.2 | 60.9 ± 6.3 | 64.3 ± 3.8 |
Smoking, pack years | 80.0 ± 14.1††| 50.7 ± 6.2†| 0 ± 0 |
FEV1, liters | 0.91 ± 0.11** | 2.35 ± 0.17 | 2.14 ± 0.12 |
FEV1/FVC, % | 34.0 ± 3.4** | 75.4 ± 2.9 | 75.0 ± 4.3 |
FEV1, % predicted | 35.5 ± 4.0** | 91.0 ± 6.4 | 101.2 ± 5.4 |