From: Expansion of CD4+CD25+helper T cells without regulatory function in smoking and COPD
Never-smokers n = 9 | Smokers n = 14 | COPD Ex-smokers n = 4 | COPD Smokers n = 5 | |
---|---|---|---|---|
Male:Female | 5:4 | 7:7 | 4:0 | 0:5 |
Age | 65 ± 5.2 | 60 ± 6.6 | 67 ± 2.1 | 61 ± 2.4 |
Smoking (pack years) | 0 (0-0) | 30 (20-44) | 50 (44-52) | 46 (35-65) |
COPD stage (GOLD) + | NA | NA | 2 and 3 | 2 and 3 |
FEV 1 /FVC % Pre bronchodilatation | 77 (74-83) | 78 (75-82) | 62 (60-67) | 60 (56-67) |
FEV 1 /FVC % Post bronchodilatation | NA | 78 (77-81) | 64 (62-67) | 60 (59-66) |
FEV 1 % of predicted Pre bronchodilatation | 101 (89-110) | 112 (104-120) | 53 (40-64) | 53 (47-66) |
FEV 1 % of predicted Post bronchodilatation | NA | 114 (108-119) | 63 (52-67) | 60 (55-68) |