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Table 3 The association of IL8 SNPs with the risk of idiopathic pulmonary fibrosis (IPF) by gender

From: A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode

Male     Female    
MAF   OR(95%CI)* P* MAF   OR(95%CI)* P*
IPF and Clinical IPF (n = 152) NC (n = 178)    IPF and Clinical IPF (n = 70) NC (n = 276)   
0.340 0.394 0.51 (0.26-0.97) 0.04 0.331 0.351 0.53 (0.18-1.57) 0.25
0.336 0.394 0.49 (0.26-0.93) 0.03 0.336 0.350 0.57 (0.20-1.64) 0.30
0.288 0.326 0.83 (0.39-1.75) 0.62 0.316 0.297 0.64 (0.19-2.24) 0.49
0.064 0.071 . . 0.008 0.054 . .
  1. * Logistic models were used for calculating odd ration and p-values in recessive model controlling for age, sex, and smoking status as covariates.
  2. NC: normal controls
  3. MAF: Minor allele frequency
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Respiratory Research

ISSN: 1465-993X

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