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Table 3 The association of IL8 SNPs with the risk of idiopathic pulmonary fibrosis (IPF) by gender

From: A promoter SNP rs4073T>A in the common allele of the interleukin 8 gene is associated with the development of idiopathic pulmonary fibrosis via the IL-8 protein enhancing mode

Male

   

Female

   

MAF

 

OR(95%CI)*

P*

MAF

 

OR(95%CI)*

P*

IPF and Clinical IPF (n = 152)

NC (n = 178)

  

IPF and Clinical IPF (n = 70)

NC (n = 276)

  

0.340

0.394

0.51 (0.26-0.97)

0.04

0.331

0.351

0.53 (0.18-1.57)

0.25

0.336

0.394

0.49 (0.26-0.93)

0.03

0.336

0.350

0.57 (0.20-1.64)

0.30

0.288

0.326

0.83 (0.39-1.75)

0.62

0.316

0.297

0.64 (0.19-2.24)

0.49

0.064

0.071

.

.

0.008

0.054

.

.

  1. * Logistic models were used for calculating odd ration and p-values in recessive model controlling for age, sex, and smoking status as covariates.
  2. NC: normal controls
  3. MAF: Minor allele frequency
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Respiratory Research

ISSN: 1465-993X

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