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Table 1 Demographic and baseline characteristics of health outcomes population and all randomized patients (efficacy population)

From: Health status in the TORCH study of COPD: treatment efficacy and other determinants of change

Variable Placebo
(n = 1231)
SAL
(n = 1232)
FP
(n = 1248)
SFC
(n = 1240)
Total HO population
(n = 4951)
Total population
(n = 6112)
Age at enrollment (years) 65.0 (8.2) 65.2 (8.2) 65.0 (8.5) 65.0 (8.3) 65.1 (8.3) 65.0 (8.3)
Male gender (%) 921 (75) 926 (75) 923 (74) 912 (74) 3682 (74) 4631 (76)
BMI (kg/m2) 25.8 (5.2) 25.7 (5.1) 25.6 (5.2) 25.6 (5.3) 25.7 (5.2) 25.4 (5.18)
Geographical region (%)       
USA 342 (27.8) 344 (27.9) 348 (27.9) 345 (27.8) 1379 (27.9) 1388 (22.7)
Asia-Pacific 89 (7.2) 93 (7.5) 95 (7.6) 93 (7.5) 370 (7.5) 758 (12.4)
Eastern Europe 185 (15) 186 (15.1) 185 (14.8) 184 (14.8) 740 (14.9) 1154 (18.9)
Western Europe 410 (33.3) 405 (32.9) 413 (33.1) 409 (33) 1637 (33.1) 1908 (31.2)
Other 205 (16.7) 204 (16.6) 207 (16.6) 209 (16.9) 825 (16.7) 935 (15.3)
Current smoker (%) 538 (44) 536 (44) 543 (44) 539 (43) 2156 (44) 2630 (43)
Pack-years smoked 49.5 (27.5) 50.6 (28.6) 50.0 (28.8) 47.7 (26.6) 49.4 (27.9) 48.5 (27.4)
Post-bronchodilator FEV1 (l)* 1.24 (0.42) 1.21 (0.40) 1.22 (0.42) 1.24 (0.43) 1.23 (0.42) 1.22 (0.42)
Post-bronchodilator FEV1 (% predicted*) 44.5 (12.3) 43.7 (12.4) 44.3 (12.3) 44.6 (12.3) 44.3 (12.3) 44.0 (12.4)
Reversibility (% predicted FEV1)* 3.7 (3.8) 3.7 (4.0) 3.6 (3.7) 3.7 (3.6) 3.7 (3.8) 3.7 (3.7)
Pre-bronchodilator FEV1/FVC ratio* 48.4 (11.0) 48.6 (11.0) 48.1 (10.8) 48.1 (10.8) 48.3 (10.9) 48.6 (10.8)
Baseline SGRQ total score 49.0 (17.4) 49.9 (16.6) 49.5 (17.1) 48.9 (17.4) 49.3 (17.1) -
  1. Data are mean (standard deviation) unless otherwise indicated
  2. *Data are from visit one (screening)
  3. BMI = body mass index; FP = fluticasone propionate; FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; HO = health outcomes; SAL = salmeterol; SFC = salmeterol+fluticasone propionate; SGRQ = St George's Respiratory Questionnaire