Respiratory Research

Table 2 Claudin expression changes in different lung pathologies

From: Claudins in lung diseases

	UIP*	ARDS	Inflammation	Lung SQC**	Lung AC**	Lung SCC**	Reference
CL1	↑		↔	↑↔	↔↔	↔	[37, 18, 81, 82, 47, 76, 77]
Cl2	↑		↓	↔↔	↔↔	↔	[15, 18, 81, 82]
CL3	↑		↓	↔↔	↔↔	↑	[18, 81, 82, 82]
CL4	↑	↓	↓↔	↔↔	↑↑	↑	[15, 18, 37, 68–70, 81, 82]
CL5	↑	↓	↓	↓	↓		[15, 68–70, 81, 82]
CL7	↑			↔↔	↑↔	↔	[18, 81, 82, 82]

CL = Claudin; UIP = Usual interstitial pneumonia; ARDS = acute respiratory distress syndrome; SQC = Squamous cell carcinoma; AC = Adenocarcinoma; SCC = Small cell carcinoma
* = arrows represent metaplastic alveolar cells
** = qtRNA results compared with lung tissue expression

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ISSN: 1465-993X

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