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Table 3 Pulmonary function and 6-Minute-walk-distance characteristics of 10 patients with lymphangioleiomyomatosis

From: Is sirolimus a therapeutic option for patients with progressive pulmonary lymphangioleiomyomatosis?

Pat. # DLCO (% pred.) pO2(mmHg) 6 MWD (m)
  baseline 3 months p 6 months p baseline 3 months p 6 months p baseline 6 months p
1 46    51   68 67   68   700 730  
2 38 37   38   61 67   69   500 530  
3 37    40   62 67   69     
4 26 33   39   55 56   62   420 510  
5 15 12   18   52 41   48     
6 23 25   24   69 67   70   510 535  
7 12 15   19   55 50   56   300 370  
8 22    30   59    63     
9 34 36   36   60 62   56   525   
10 27 32   32   57 64   68    540  
Mean ± SEM 28.0 ± 3.4 27.1 ± 3.8 0.15 32.7 ± 3.3 0.004 59.8 ± 1.7 60.1 ± 3.1 0.91 62.9 ± 2.3 0.88 486 ± 65 535 ± 57 0.02
  1. Definition of abbreviations: FEV1 = forced expiratory volume in 1 second, FVC = forced vital capacity, DLCO = single breath diffusing capacity for carbon monoxide, pO2 = partial pressure of oxygen, 6-MWD = 6-Minute-Walk-Distance, SEM = standard error of the mean.