Skip to main content

Table 3 Pulmonary function and 6-Minute-walk-distance characteristics of 10 patients with lymphangioleiomyomatosis

From: Is sirolimus a therapeutic option for patients with progressive pulmonary lymphangioleiomyomatosis?

Pat. #

DLCO (% pred.)

pO2(mmHg)

6 MWD (m)

 

baseline

3 months

p

6 months

p

baseline

3 months

p

6 months

p

baseline

6 months

p

1

46

  

51

 

68

67

 

68

 

700

730

 

2

38

37

 

38

 

61

67

 

69

 

500

530

 

3

37

  

40

 

62

67

 

69

    

4

26

33

 

39

 

55

56

 

62

 

420

510

 

5

15

12

 

18

 

52

41

 

48

    

6

23

25

 

24

 

69

67

 

70

 

510

535

 

7

12

15

 

19

 

55

50

 

56

 

300

370

 

8

22

  

30

 

59

  

63

    

9

34

36

 

36

 

60

62

 

56

 

525

  

10

27

32

 

32

 

57

64

 

68

  

540

 

Mean ± SEM

28.0 ± 3.4

27.1 ± 3.8

0.15

32.7 ± 3.3

0.004

59.8 ± 1.7

60.1 ± 3.1

0.91

62.9 ± 2.3

0.88

486 ± 65

535 ± 57

0.02

  1. Definition of abbreviations: FEV1 = forced expiratory volume in 1 second, FVC = forced vital capacity, DLCO = single breath diffusing capacity for carbon monoxide, pO2 = partial pressure of oxygen, 6-MWD = 6-Minute-Walk-Distance, SEM = standard error of the mean.