Figure 4From: GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cellsGDF-15 immunohistochemistry in a concentric lesion of a patient with PAH. Immunoreactiv-ity for GDF-15 is observed in cells lining the small remaining lumen of the concentric lesion (asterisk). Inset depicts a high-power view of the GDF-15 positive cells, which are probably endothelial cells (arrowheads). Original magnifications: × 200; Inset × 400.Back to article page