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Figure 3 | Respiratory Research

Figure 3

From: GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

Figure 3

GDF-15 immunohistochemistry in pulmonary arterial hypertension (PAH). GDF-15 protein expression in PAH) showing a strong signal in the endothelial cell layer (arrows) of a pulmonary artery with media hypertrophy. The smooth muscle cells (arrowheads) of the remodeled pulmonary artery are lacking significant GDF-15 protein expression. Macrophages around the pulmonary artery stain positive for GDF-15 (asterisks). Original magnification: × 200.

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