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Figure 2 | Respiratory Research

Figure 2

From: GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

Figure 2

GDF-15 immunohistochemistry in normal human lung tissue. Note the staining of endothelial cells in small pulmonary arteries (arrow). Insets depicts a high-power view, highlighting the expression of GDF-15 in endothelial cells. Smooth muscle cells exhibit a weaker signal (arrowhead). Alveolar macrophages show a strong signal for GDF-15 (asterisks). A weak signal for GDF-15 was noted in alveolar and bronchial epithelial cells. Original magnifications: × 100; Inset a × 200, inset b × 300.

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