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Figure 13 | Respiratory Research

Figure 13

From: GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

Figure 13

Akt phosphorylation by GDF-15 in endothelial cells. GDF-15 induced Akt phosphorylation at Ser437 in human pulmonary microvascular endothelial cells (HPMEC). The cells were stimulated with recombinant GDF-15 protein (50 ng/ml) for 30 to 240 minutes. Akt and Ser437 were determined by immunoblotting. An exemplary blot from n = 3 experiments is presented.

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Respiratory Research

ISSN: 1465-993X

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