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Table 1 Respiratory tissue parameters under baseline conditions, during MCh infusion at a dose of 24 μg/kg/min, and their percentage changes in the different groups

From: Prevention of bronchial hyperreactivity in a rat model of precapillary pulmonary hypertension

 

G (cmH2O/l)

Change in G

H (cmH2O/l)

Change in H

 

Baseline

MCh 24 μg/kg/min

%

Baseline

MCh 24 μg/kg/min

%

CC

866 ± 49

1150 ± 76*

33 ± 5

2927 ± 299

3767 ± 334*

31 ± 4

CS

736 ± 42

968 ± 78*

31 ± 5

2936 ± 167

3329 ± 195*

15 ± 6

VIP

735 ± 33

991 ± 49*

37 ± 10

2589 ± 258

3139 ± 231*

24 ± 5

ILO

802 ± 84

930 ± 65*

21 ± 9

2972 ± 397

3061 ± 147

10 ± 10

SIL

964 ± 45

1159 ± 50*

21 ± 6

3240 ± 281

3741 ± 278*

16 ± 3

TEZ

727 ± 34

911 ± 58*

25 ± 3

2370 ± 156

3001 ± 232*

26 ± 2

  1. CC: control group, CS: shunt, no treatments, VIP: shunt, treatment with VIP, ILO: shunt, treatment with iloprost, SIL: shunt, treatment with sildenafil, TEZ: shunt, treatment with tezosentan.
  2. *: p < 0.05 vs. the value obtained under baseline conditions within a group.