Figure 5
From: Prevention of bronchial hyperreactivity in a rat model of precapillary pulmonary hypertension
Equivalent dose required to cause a 50% increase in airway resistance (ED 50 ) in the different groups. CC: control group, CS: shunt, no treatments, VIP: shunt, treatment with VIP, ILO: shunt, treatment with iloprost, SIL: shunt, treatment with sildenafil, TEZ: shunt, treatment with tezosentan. *: p < 0.05 vs. the data obtained in the rats with precapillary pulmonary hypertension without drug treatment (Group CS).