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Table 5 Genotype distribution of MMP2 and TIMP1 SNPs in Vlagtwedde/Vlaardingen and Doetinchem.

From: Genetic variation in TIMP1 but not MMPs predict excess FEV1 decline in two general population-based cohorts

  

Vlagtwedde/Vlaardingen N (%)

Doetinchem N (%)

P value

     

MMP2 C-1306T

CC

734 (53.0)

609 (55.1)

0.055

     
 

CT

552 (39.9)

443 (40.1)

      
 

TT

98 (7.1)

53 (4.8)

      
  

FEMALES

   

MALES

 
  

Vlagtwedde/Vlaardingen N (%)

Doetinchem N (%)

P value

  

Vlagtwedde/Vlaardingen N (%)

Doetinchem N (%)

P value

TIMP1 Ile158Ile

CC

636 (98.0)

602 (99.2)

0.079

TIMP1 Ile158Ile

C

686 (99.0)

526 (99.4)

0.394

 

CT

13 (2.0)

5 (0.8)

  

T

7 (1.0)

3 (0.6)

 
 

TT

0 (0)

0 (0)

      

TIMP1 Phe124Phe

TT

138 (21.3)

135 (23.4)

0.657

TIMP1 Phe124Phe

T

336 (49.6)

240 (47.6)

0.494

 

TC

338 (52.0)

295 (51.1)

  

C

341 (50.4)

264 (52.4)

 
 

CC

173 (26.7)

147 (25.5)

      
  1. TIMP1 SNP distributions are stratified by sex.