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Table 1 Characteristics of the Vlagtwedde/Vlaardingen and Doetinchem cohorts

From: Genetic variation in TIMP1 but not MMPs predict excess FEV1 decline in two general population-based cohorts

 

Vlagtwedde/Vlaardingen N = 1390

Doetinchem N = 1152

Age at last survey, yrs

52 (35-79)

50 (31-71)

Males, %

51

47

Pack-years

9.0 (0-262.1)

5 (0-84)

Never smokers, n (%)

445 (32.0)

371 (32.2)

last FEV1%pred*

93.5 (36.0-138.1)

106.6 (39.1-150.7)

ΔFEV1, ml/yr†

-21.1 (-121;155)

-28.7 (-292; 130)

FEV1 values, n

7 (1-8)

2 (2-2)

Yrs of follow-up

21 (0-25)

5 (5-5)

GOLD stage > II,n (%)

186 (13.4)

37 (3.2)

  1. Data are presented as median (range)
  2. * FEV1 % predicted at the last surveys of Vlagtwedde/Vlaardingen cohort (1989/1990) and the Doetinchem cohort (1999-2003)
  3. † calculated as last-first FEV1/years participated