Figure 2

Table 2. Histological alterations (A,B,C) and chimerism (D,E,F) in bronchial allografts (A,B,D,E) and in a control autograft (C,F). Epithelial damage is observed in a bronchial allograft on follow-up day 4 (A) and recovered epithelium and bronchial wall structure on day 7 in an adequately treated allograft (B). H&E, original magnification ×10. Recovery of the adequately treated allograft (B) was similar to that of a control autograft (C) on day 7. H&E, original magnification ×10. Tissue section of a bronchial allograft of female origin in a male recipient hybridized with probes for pig chromosomes Y (red) and 1 (green) on day 7 (D) shows epithelial and bronchial wall cells with Y chromosomes. Y chromosomes are more frequent on follow-up day 10 (E) than on follow-up day 7 (D) in recovered epithelium in adequately treated allografts. Chromosomes Y (red) and 1 (green) stain invariably (F) in a male control autograft on follow-up day 7 and confirm successful hybridization. Staining with 4',6-diamidino-2-phenylindole, original magnification ×1000.