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Table 2 Posterior summaries for parameters from the model of trough FEV1 at steady state in the study-level analysis

From: Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using model-based approaches

  Mean SD Q2.5 Q50 (median) Q97.5
Model parameters      
Emax (mL) 177 13 152 176 206
ED50 (μg) 28 10 12 26 52
Derived parameters      
ED90 (μg) 110 41 46 105 207
Effect as percentage of maximum effect
18.75 μg 42 9 27 42 62
37.5 μg 59 9 42 59 76
75 μg 74 7 59 74 87
150 μg 85 5 74 85 93
300 μg 92 3 85 92 96
600 μg 96 2 92 96 98
  1. Q2.5 and Q97.5 are the 2.5th and 97.5th quantiles, respectively, and correspond to the 95% CI for each parameter. SD = standard deviation.