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Table 2 Posterior summaries for parameters from the model of trough FEV1 at steady state in the study-level analysis

From: Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using model-based approaches

 

Mean

SD

Q2.5

Q50 (median)

Q97.5

Model parameters

     

Emax (mL)

177

13

152

176

206

ED50 (μg)

28

10

12

26

52

Derived parameters

     

ED90 (μg)

110

41

46

105

207

Effect as percentage of maximum effect

18.75 μg

42

9

27

42

62

37.5 μg

59

9

42

59

76

75 μg

74

7

59

74

87

150 μg

85

5

74

85

93

300 μg

92

3

85

92

96

600 μg

96

2

92

96

98

  1. Q2.5 and Q97.5 are the 2.5th and 97.5th quantiles, respectively, and correspond to the 95% CI for each parameter. SD = standard deviation.