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Table 3 Multivariate adjusted odds ratio of death for selected variables on day 1, day 6 and the change in each variable between day 1 and day 6

From: Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury

  

Day 1

  

Day 6

 

Δ Day 1 ➔ Day 6

Variable

OR*

95% CI

P

OR*

95% CI

P

OR*

95% CI

P

PaO2/FiO2

1.02

0.55-1.87

0.96

2.09

1.05-4.15

0.04

1.71

0.94-3.12

0.08

OI

2.16

1.24-3.76

0.01

1.75

0.91-3.36

0.09

1.28

0.74-2.23

0.37

Crs

0.88

0.51-1.51

0.64

3.61

1.32-9.84

0.01

2.14

1.12-4.11

0.02

BD

0.77

0.41-1.43

0.4

1.45

0.77-2.72

0.25

1.72

0.94-3.15

0.08

  1. * ORs of death are per standard deviation (SD) decrease for PaO2/FiO2, Crs, or BD and per standard deviation increase for OI.
  2. Definition of abbreviations: OI, oxygenation index; Crs, quasistatic respiratory system compliance; BD, base deficit; OR, odds ratio; CI, confidence interval; p values <0.05 considered significant. Description of model: Stepwise, backward, multivariate logistic regression, p-values <0.1 remained in model and included: age, gender, COPD, pneumonia, vasopressors, APACHEII, worse pH on day 1. The main variables (PaO2/FiO2, OI, Crs, BD) were maintained in the final model regardless of p-value.
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Respiratory Research

ISSN: 1465-993X

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