Table 1 Baseline characteristics of 93 patients who survived more than 6 days of mechanical ventilation for ALI
| Â | All Patients (n = 93) | Survivors (n = 60) | Non-Survivors (n = 33) | P value (S vs. NS) |
|---|---|---|---|---|
Age (Mean (SD)) | 46.4 (16.5) | 42.0 (13.3) | 54.3 (18.8) | <0.001 |
SAPS II | 41.9 (14.2) | 37.9 (14.2) | 49.1 (11.0) | <0.001 |
APACHE II score | 18.7 (7.1) | 17.0 (7.3) | 21.5 (5.85) | <0.01 |
LISS | 2.65 (0.50) | 2.62 (.05) | 2.71 (0.5) | 0.46 |
Lowest MAP | 61.6 (11.4) | 62.4 (11.5) | 59.9 (11.3) | 0.35 |
PaO2 | 105.4 (47) | 105.4 (45.6) | 105.2 (50.2) | 0.98 |
PaCO2 | 43.2 (9.6) | 42.7 (7.6) | 44.1 (12.4) | 0.48 |
FiO2 | 0.76 (0.24) | 0.74 (0.25) | 0.80 (0.21) | 0.27 |
A-a Gradient | 363 (182) | 343.5 (191.3) | 398.3 (160.3) | 0.17 |
PaO2/FiO2 | 147 (60) | 151.3 (58.8) | 138.4 (62.3) | 0.34 |
OI (cmH20/mm Hg) | 11.4 (8.0) | 10.0 (5.8) | 13.9 (10.45) | 0.02 |
Respiratory system compliance (ml/cm H20) | 27.8 (10.4) | 27.6 (8.8) | 28.1 (13.0) | 0.84 |
Tidal Volume (ml) | 474.0 (125.6) | 490.8 (116.3) | 442.6 (137.8) | 0.08 |
Tidal Volume (ml/kg PBW) | 7.4 (2.2) | 7.8 (1.9) | 6.7 (2.5) | 0.02 |
Duration of Mechanical Ventilation | 21.4 (25.1) | 20.5 (14.9) | 23.1 (37.4) | 0.64 |
pH | 7.33 (0.10) | 7.34 (0.09) | 7.31 (0.11) | 0.16 |
Base Deficit | -3.34 (5.98) | -2.94 (5.94) | -4.05 (6.08) | 0.40 |
Gender (% female) | 32% | 29% | 36% | 0.63 |
Primary cause of ARDs | 41% | 43% | 36% | 0.65 |
Smoker | 29% | 32% | 24% | 0.48 |
Steroid use | 17% | 13% | 24% | 0.25 |
Trauma | 8% | 12% | 0% | <0.05 |
Cirrhosis | 11% | 8% | 15% | 0.32 |
COPD | 10% | 8% | 12% | 0.72 |
Vasopressor | 46% | 35% | 64% | 0.01 |