Figure 5
From: Pulmonary arterial dysfunction in insulin resistant obese Zucker rats
Vasoconstrictor responses in resistance PA. (A) Contractile responses of resistance PA induced by KCl (80 mM, n = 8, left), hypoxia (n = 3, middle) and phenyleprine (10-7 M, n = 3-4, right) in resistance PA from lean and obese Zucker rats. (B) Concentration-response curve to 5-HT (n = 6). (C) Whole lung protein expression of 5-HT2A receptor (n = 8). Results indicate mean ± s.e.m. *, ** denote P < 0.05 and P < 0.01 respectively, obese vs lean.