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Table 3 Association between high blood pressure, antihypertensive medication and lung function - results of the multivariable regression analysis

From: High blood pressure, antihypertensive medication and lung function in a general adult population

Models for FEV1(L)

   

Models for FVC (L)

   

Nr.

Variable

Estimate

SD

P #

Variable

Estimate

SD

P #

 

HBP and antihypertensive medication classes

HBP and antihypertensive medication classes

1.

HBP

-0.09

0.04

0.02

HBP

-0.11

0.04

0.01

2.

HBP or medication

-0.08

0.03

0.01

HBP or medication

-0.10

0.03

<0.01

3.

Medication

-0.07

0.04

0.05

Medication

-0.08

0.04

0.05

 

Models with mutual exclusive categories

Models with mutual exclusive categories

4.

No HBP, no medication§

  

No HBP, no medication§

  
 

HBP and medication

-0.16

0.06

0.02

HBP and medication

-0.17

0.07

0.02

 

Only HBP

-0.08

0.04

0.09

Only HBP

-0.10

0.05

0.04

 

Only medication

-0.06

0.04

0.14

Only medication

-0.07

0.05

0.12

5.

No anti-hypertensive drugs§

  

No anti-hypertensive drugs§

  
 

Beta blocker

-0.08

0.05

0.07

Beta blocker

-0.11

0.05

0.03

 

Other anti-hypertensive drugs

-0.06

0.05

0.28

Other anti-hypertensive drugs

-0.04

0.06

0.51

5a.

No anti-hypertensive drugs§

  

No anti-hypertensive drugs§

  
 

Beta blocker

-0.08

0.05

0.07

Beta blocker

-0.10

0.05

0.04

 

Other anti-hypertensive drugs

-0.04

0.05

0.41

Other anti-hypertensive drugs

-0.02

0.06

0.72

 

HBP

-0.08

0.04

0.03

HBP

-0.10

0.04

0.01

 

HBP and antihypertensive medication as individual variables

HBP and antihypertensive medication as individual variables

6.

HBP

-0.08

0.04

0.03

HBP

-0.10

0.04

0.02

 

Medication

-0.07

0.04

0.08

Medication

-0.07

0.04

0.08

  1. Multivariable regression analysis using the high blood pressure and antihypertensive medication classes (Model 1-3), mutual exclusive categories (Model 4,5,5a) and high blood pressure and antihypertensive medication as individual variables (Model 6).
  2. SD: standard deviation; FEV1: forced expiratory volume in one second; FVC: forced vital capacity; HBP: high blood pressure (≥140/90 mmHg); Medication: antihypertensive medication; § Reference category; #P-Value: all models are adjusted for gender, age, height, weight, education level, packyears, pulmonary and cardiac diseases.