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Table 1 Characteristics and lung function data in COPD patients, smoking controls (S) and non-smoking controls (NS).

From: Tenascin-C and alpha-smooth muscle actin positive cells are increased in the large airways in patients with COPD

 

COPD

S

NS

N (n)

20

13

14

Males (n)

11

6

7

Age (years)

56 ± 5

55 ± 7

57 ± 4

Pack-years (years)

34 (24-43)###

36 (27-37)†††

0

FEV1/FVC

0.54

(0.38-0.52) ***###

0.80 (0.76-0.81)

0.84 (0.83-0.84)

FEV1/VC

0.48

(0.52-0.62) ***###

0.79 (0.75-0.83)

0.77 (0.76-0.80)

FEV1 (L)

1.58

(1.22-1.94) ***###

2.89 (2.71-3.57)

3.32 (2.75-3.94)

FEV 1 (% predicted)

53 (47-60)***###

98 (95-104)†

109 (106-121)

FEV 1 reversibility (%)

14 (4-19)***###

4 (0-5)

2 (0-3)

FEV 1 reversibility (mL)

190 (75-265)#

90 (0-170)

70 (8-105)

  1. Data are shown as mean and standard deviation for age, mean and inter quartile range for pack-years, median and inter quartile range for all others. Significant difference between groups is marked with * (COPD vs HS), # (COPD vs NS) and † (HS vs NS). The considered levels of significance were P < 0.05 (*, # or †), P < 0.01 (**, ## or ††) and P < 0.001 (***, ### or †††). FEV1: Forced expiratory volume in one second, measured post bronchodilation; FVC: Forced vital capacity; VC: Vital capacity.
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Respiratory Research

ISSN: 1465-993X

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