Figure 4From: A new pathway of glucocorticoid action for asthma treatment through the regulation of PTEN expressionEffect of anacardic acid, dexamethasone and TSA on PTEN expression in A549 cells. Cells were incubated with dexamethasone (10-5 M), the HAT inhibitor anacardic acid (20 μmol/L) plus dexamethasone (10-5 M), anacardic acid (20 μmol/L) or TSA(1 μmol/L) for 24 h. The PTEN mRNA level was measured by quantitative real-time PCR. A representative of three separate experiments is shown. #p = 0.006 vs control group; *#p = 0.0469 vs Dex+Ana group; **p > 0.05 vs control group.Back to article page