Figure 4

Secretion of TNF-α by transplant-derived airway epithelial cells after stimulation with IL-1β and cyclosporine. A. TNF-α secretion in basal medium after basal stimulation. *, P < 0.0001 for IL-1β vs. control and for IL-1β and cyclosporine vs. cyclosporine alone. B. TNF-α secretion in basal medium after apical stimulation. *, P = 0.0001 for IL-1β vs. control and for IL-1β and cyclosporine vs. cyclosporine alone. N = 5 unique patient samples except for apical stimulation with both IL-1β and cyclosporine, for which N = 3.