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Figure 3 | Respiratory Research

Figure 3

From: Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation

Figure 3

Cigarette smoke induced BRP-39 production is IL-1 dependent. WT BALB/c and IL-13 KO mice were room air (white bars) or cigarette smoke-exposed (black bars). (A) Data show total cell numbers (TCN), mononuclear cells (MNC), and neutrophils (NEU) in the BAL as well as BRP-39 expression in lung homogenates. WT C57BL/6 and IL-1R1 KO (B) or IL-18 KO (C) mice were room air or cigarette smoke-exposed with the same corresponding readouts. (D) Immunohistochemistry was performed to identify the localization of BRP-39 expression in WT and IL-1R1 KO mice. n = 5, data shown in B are representative of 2 separate experiments, * indicate P < 0.05.

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Respiratory Research

ISSN: 1465-993X

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