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Table 2 Baseline characteristics of COPD patients in relation to the presence and severity of emphysema

From: Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study

Characteristics No or mild (n = 119) Moderate to severe (n = 81) P-value
Age, years 66 (60-69) 67 (62-71) 0.475
Male sex 105 (88) 73 (90) 0.819
BMI (kg/m2) 29 (26-31) 25 (23-27) <0.001
Current smoker 60 (50) 37 (46) 0.565
Pack-years of smoking 46 (38-59) 50 (40-60) 0.152
FEV1, % predicted 60 (51-66) 42 (32-53) <0.001
DLCO, % predicted 83 (74-97) 57 (47-71) <0.001
Chronic mucous hypersecretion 65 (55) 51 (63) 0.248
Chronic cor pulmonale 16 (13) 31 (38) <0.001
QoL questionnaire, total score 28 (19-41) 40 (21-60) 0.009
Comorbidity    
Systemic arterial hypertension 67 (56) 28 (35) 0.004
Coronary artery disease 37 (31) 22 (27) 0.636
Heart failure 12 (10) 11 (14) 0.502
Diabetes mellitus 15 (13) 7 (9) 0.492
Dyslipidemia 44 (37) 17 (21) 0.019
Therapy    
Inhaled bronchodilators 74 (62) 65 (80) 0.008
Inhaled corticosteroids 71 (60) 57 (70) 0.135
Oral theophylline 22 (18) 26 (32) 0.030
Cardiovascular drugs 80 (67) 42 (52) 0.039
Diuretics 28 (24) 24 (30) 0.412
Statins 25 (21) 12 (15) 0.354
  1. Data are reported as median (interquartile range), or number (%).
  2. Definitions of abbreviations: QoL = quality of life.
  3. For the other abbreviations see table 1.