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Table 1 Baseline characteristics of the study sample

From: Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study

Characteristics

COPD (n = 200)

No COPD (n = 201)

P-value

Age, years

66 (61-70)

65 (61-70)

0.258

Male sex

178 (89)

172 (86)

0.369

BMI (kg/m2)

27 (24-31)

28 (25-30)

0.508

Current smoker

97 (49)

101 (50)

0.766

Pack-years of smoking

48 (39-60)

40 (33-50)

<0.001

FEV1, % predicted

54 (42-65)

95 (88-105)

<0.001

DLCO, % predicted

76 (58-86)

96 (86-108)

<0.001

Chronic mucous hypersecretion

116 (58)

46 (23)

<0.001

Chronic cor pulmonale

47 (24)

0 (0)

<0.001

Emphysema

87 (44)

0 (0)

<0.001

Comorbidity

   

Systemic arterial hypertension

95 (48)

75 (37)

0.043

Coronary artery disease

59 (30)

55 (27)

0.659

Heart failure

23 (12)

13 (6.5)

0.083

Dilated cardiomyopathy

6 (3)

6 (3)

1.000

Left heart valvular disease

8 (4)

5 (2.5)

0.416

Chronic atrial fibrillation

10 (5)

7 (3.5)

0.470

Prior stroke

2 (1)

3 (1.5)

1.000

Prior PE or DVT

5 (2.5)

3 (1.5)

0.503

Renal failure

0 (0)

0 (0)

1.000

Diabetes mellitus

22 (11)

30 (15)

0.298

Dyslipidemia

61 (31)

74 (37)

0.205

Thyroid dysfunction

18 (9)

11 (5.5)

0.183

Chronic hepatitis C

7 (3.5)

9 (4.5)

0.799

Therapy

   

Inhaled bronchodilators

139 (70)

0 (0)

<0.001

Inhaled corticosteroids

128 (64)

0 (0)

<0.001

Oral theophylline

48 (24)

0 (0)

<0.001

Long-term oxygen

7 (3.5)

0 (0)

0.007

Cardiovascular drugs

122 (61)

108 (54)

0.158

Diuretics

52 (26)

30 (15)

0.006

Warfarin

15 (8)

10 (5)

0.311

Statins

37 (19)

47 (23)

0.269

Oral hypoglicemic drugs/insulin

17 (9)

21 (10)

0.609

Thyroid replacement therapy

7 (3.5)

4 (2)

0.380

  1. Data are reported as median (interquartile range), or number (%).
  2. Definitions of abbreviations: BMI = body mass index; FEV1 = forced expiratory volume in one second; DLCO = diffusing capacity of the lung for carbon monoxide; PE = pulmonary embolism; DVT = deep vein thrombosis.