Skip to main content

Table 3 Multivariate linear regression modules for factors associated with depression

From: Biomarkers of systemic inflammation and depression and fatigue in moderate clinically stable COPD

Module 1 Module 2
Variables Beta p Variables Beta p
TNF-α 0.26 0.007 TNF-α 0.23 0.024
CRP 0.07 0.5 TNF-α-R1 -0.13 0.3
TNF-α-R1 -0.1 0.5 TNF-α-R2 -0.13 0.3
TNF-α-R2 -0.2 0.2 6MWD -0.22 0.027
IL-6 -0.2 0.1 FEV1% 0.02 0.9
    Pack/years -0.02 0.9
  1. *BASDEC depression score was the dependent variable
  2. CRP = C-reactive protein; FEV 1 = Forced Expiratory Volume over 1 Second; IL-6 = Interleukin-6; 6MWD = 6 Minute Walk Distance; TNF-α = Tumor necrosis factor-α; TNF-α R1 = Tumor necrosis factor-α receptor1; TNF-α R2 = Tumor necrosis factor-α receptor2.