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Table 3 Multivariate linear regression modules for factors associated with depression

From: Biomarkers of systemic inflammation and depression and fatigue in moderate clinically stable COPD

Module 1

Module 2

Variables

Beta

p

Variables

Beta

p

TNF-α

0.26

0.007

TNF-α

0.23

0.024

CRP

0.07

0.5

TNF-α-R1

-0.13

0.3

TNF-α-R1

-0.1

0.5

TNF-α-R2

-0.13

0.3

TNF-α-R2

-0.2

0.2

6MWD

-0.22

0.027

IL-6

-0.2

0.1

FEV1%

0.02

0.9

   

Pack/years

-0.02

0.9

  1. *BASDEC depression score was the dependent variable
  2. CRP = C-reactive protein; FEV 1 = Forced Expiratory Volume over 1 Second; IL-6 = Interleukin-6; 6MWD = 6 Minute Walk Distance; TNF-α = Tumor necrosis factor-α; TNF-α R1 = Tumor necrosis factor-α receptor1; TNF-α R2 = Tumor necrosis factor-α receptor2.