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Figure 1 | Respiratory Research

Figure 1

From: The cytokine-driven regulation of secretoglobins in normal human upper airway and their expression, particularly that of uteroglobin-related protein 1, in chronic rhinosinusitis

Figure 1

The effect of cytokines on secretoglobins (SCGBs) mRNA expression in ex vivo cultured normal nasal mucosa. For dose response experiments, the normal inferior turbinate tissues were incubated in the presence of TNF-α (1, 10, and 100 ng/ml), IL-1β (1, 10, and 100 ng/ml), INF-γ (0.1, 1, and 10 ng/ml), IL-4 (1, 10, and 100 ng/ml), or IL-13 (1, 10, and 100 ng/ml) for 12 h. For time course experiments, the tissues were incubated with TNF-α (20 ng/ml), IL-1β (20 ng/ml), IL-4 (20 ng/ml), IL-13 (20 ng/ml), or INF-γ (1 ng/ml) for various time durations between 4 and 24 h. n = 6. Results are expressed as mean ± SD. #P < 0.05 and *P < 0.01 compared with untreated mucosa.

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Respiratory Research

ISSN: 1465-993X

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