Figure 2

Representative photomicrographs of right lower lung sections and RV hypertrophy index. Lung sections in the control group showed normal architecture. Lung sections from the MCT-treated group showed tissue damage characterized by a thicker pulmonary artery wall, lumen stenosis, and inflammatory cell infiltration. Lung sections from rats treated with hydrogen-rich saline (5 ml/kg once daily for 2 or 3 weeks) showed significantly less histological alteration. Sections were stained with H-E (200×) (A). Administration of hydrogen-rich saline significantly reduced RV hypertrophy compared to the MCT-treated group (B). *P < 0.05, **P < 0.01.