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Table 2 Baseline T-cell co-receptor and cytokine expression

From: Differences in allergen-induced T cell activation between allergic asthma and rhinitis: Role of CD28, ICOS and CTLA-4

 

Controls (n = 20)

R (n = 18)

AR (n = 18)

A (n = 13)

CD3+IL-4+ (%)

2.38 ± 0.26

2.88 ± 0.29

2.35 ± 0.22

3.25 ± 0.60

CD3+IL-13+ (%)

3.02 ± 0.31

4.17 ± 0.48

3.54 ± 0.34

4.18 ± 0.54

CD3+IL-10+ (%)

5.01 ± 0.47

4.06 ± 0.33

4.38 ± 0.37

4.37 ± 0.46

CD3+CD28+ (%)

87.75 ± 2.50

89.04 ± 1.71

89.50 ± 1.31

84.85 ± 3.45

  1. PBMC from each patient were cultured in complete medium during 8 days. ICOS, CD28, IL-4, IL-13, and IL-10 expression by T-cells were assessed by flow cytometry. Results are expressed as mean of total T-cells ± SE and compared versus controls. * = p < 0.05, ** = p < 0,01. R = allergic rhinitis; A R = allergic asthma and rhinitis; A = non allergic asthmatics.
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Respiratory Research

ISSN: 1465-993X

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