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Figure 3 | Respiratory Research

Figure 3

From: Differences in allergen-induced T cell activation between allergic asthma and rhinitis: Role of CD28, ICOS and CTLA-4

Figure 3

Effect of anti-co-receptors antibodies on IL-13 production by T cells. PBMC from allergic rhinitics (R) (triangle, n = 12), allergic rhinitic and asthmatics (AR) (square, n = 10) and non allergic asthmatics (A) (lozenge, n = 11) were stimulated with Derp 1 and cultured in the presence or absence of anti-ICOS, anti-CTLA-4 or anti-CD28 antibodies. IL-13 expressing T cells were then compared in each group versus baseline. Results are expressed as percentage of total T cells. Black line : mean of each group. * = p < 0.05; ** = p < 0.01; *** = p < 0.001

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