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Figure 1 | Respiratory Research

Figure 1

From: Differences in allergen-induced T cell activation between allergic asthma and rhinitis: Role of CD28, ICOS and CTLA-4

Figure 1

T cell activation and co-receptor expression before specific stimulation. CTLA-4 expression (A), Treg cells (CD4+CD25+HiFoxp3+, B), IFN-γ producing T cells (D) and ICOS expression (E) were assessed by flow cytometry in PBMC from HDM allergic rhinitics (R) (triangle, n = 18), allergic asthmatics and rhinitics (AR) (square, n = 18), non allergic asthmatics (A) (lozenge, n = 13), and controls (circle, n = 20). Treg cells were also evaluated in non allergic asthma and allergic asthma between mild and moderate asthmatics (C). Results are expressed as percentage of total T cell and compared versus controls. _ : mean of each group. * = p < 0.05; ** = p < 0.01

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