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Figure 6 | Respiratory Research

Figure 6

From: Mometasone and desloratadine additive effect on eosinophil survival and cytokine secretion from epithelial cells

Figure 6

Additive effect of mometasone and desloratadine on eosinophil survival at day 4. Human epithelial conditioned media (HECM) at 10% (dark grey bars) from nasal mucosa and nasal polyp increased eosinophil survival compared. The combination of mometasone (MF) at 10-11M and desloratadine (DL) at 10-5M (striped bars) caused an inhibitory effect higher than MF (light grey bars) or DL (white bars) alone, and similar to MF at 10-7M. This additive effect was significant when eosinophil survival was induced by nasal mucosa HECM. Results expressed as mean ± SEM of eosinophil survival index. Wilcoxon Signed Rank test was used for statistical comparison. ** p < 0.01, compared to control media; † p < 0.05, compared to HECM. N = 10.

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