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Table 3 Concentration and frequency of β-thymosins in scleroderma patients with or without alveolitis

From: β-thymosins and interstitial lung disease: study of a scleroderma cohort with a one-year follow-up

  24 scleroderma pts with alveolitis 22 scleroderma pts without alveolitis
presence of Tβ4, n pts (%) 24 (100%) 22 (100%)
4 (μmol/L, mean ± SD) 0.356 ± 0.464 0.256 ± 0.236
(median, range) (0.21, 0-2.1) (0.13, 0-1.0)
presence of sTβ4, n pts (%) 10 (41.6%) 4 (18.1%)
sTβ4 (μmol/L, mean ± SD) 0.025 ± 0.052* 0.006 ± 0.219
(median, range) (0, 0-0.24) (0, 0-0.1)
presence of Tβ10, n pts (%) 13 (54.2%) 15 (68.2%)
10 (μmol/L, mean ± SD) 0.059 ± 0.088 0.040 ± 0.049
(median, range) (0.01, 0-0.3) (0.02, 0-0.17)
4/sTβ4 ratio (mean ± SD) 7.328 ± 4.626 * 14.582 ± 4.907
  1. 4: thymosin β4; n: number; pts: patients; SD: standard deviation; sTβ4: thymosin β4 sulfoxide; Tβ10: thymosin β10.
  2. *p < 0.05: pts versus controls