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Figure 4 | Respiratory Research

Figure 4

From: Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats

Figure 4

Effect of electroporation of bone marrow cells with CXCR4 shRNA on hypoxia-induced pulmonary hypertension and vascular remodeling in rats: (A) Percent wall thickness. *p < 0.05 as compared with normoxia and hypoxic controls. # p < 0.05 as compared with normoxia and BMC+CXCR4. $p < 0.05 as compared with normoxia. (B) Body weight change. # p < 0.05 as compared with normoxia. *p < 0.05 as compared with normoxia and hypoxic controls. (C) hematocrit. *p < 0.05 as compared with normoxia control. n = 5 rats for each group. BMC = transplantation of bone marrow cells without shRNA, BMC+S-RNA = transplantation of bone marrow cells with scrambled shRNA, BMC+ CXCR4 = transplantation of bone marrow cells with CXCR4 shRNA.

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