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Table 4 Responder rates* for TDI and ΔSGRQ by average ΔFEV1 category

From: Correlating changes in lung function with patient outcomes in chronic obstructive pulmonary disease: a pooled analysis

Average ΔFEV1 (ml) Category midpoint value of ΔFEV1 (ml) TDI at 12 weeks % responders (n = 2781) TDI at 24/26 weeks % responders (n = 2208) TDI at 52 weeks % responders (n = 1099) ΔSGRQ at 12 weeks % responders (n = 3141) ΔSGRQ at 24/26 weeks % responders (n = 2215) ΔSGRQ at 52 weeks % responders (n = 1115)
-500, -50 -275 50 51 45 42 49 41
-50, 50 0 48 49 53 46 45 45
50, 150 100 54 57 50 48 48 49
150, 250 200 59 60 58 53 59 54
250, 500 375 66 69 69 56 57 65
  1. *Responders were patients who achieved at least the minimal clinically important difference (MCID; one and four units for TDI and ΔSGRQ, respectively); TDI, Transition Dyspnoea Index; ΔSGRQ, change from baseline in St George's Respiratory Questionnaire; ΔFEV1, change from baseline in trough forced expiratory volume in 1 second.
  2. For the outcomes, each row contains approximately 20% of the column's indicated n, as in the left half of Table 2