|
Average ΔFEV1 (ml)
|
Category midpoint value of ΔFEV1 (ml)
|
TDI at 12 weeks % responders (n = 2781)
|
TDI at 24/26 weeks % responders (n = 2208)
|
TDI at 52 weeks % responders (n = 1099)
|
ΔSGRQ at 12 weeks % responders (n = 3141)
|
ΔSGRQ at 24/26 weeks % responders (n = 2215)
|
ΔSGRQ at 52 weeks % responders (n = 1115)
|
|---|
|
-500, -50
|
-275
|
50
|
51
|
45
|
42
|
49
|
41
|
|
-50, 50
|
0
|
48
|
49
|
53
|
46
|
45
|
45
|
|
50, 150
|
100
|
54
|
57
|
50
|
48
|
48
|
49
|
|
150, 250
|
200
|
59
|
60
|
58
|
53
|
59
|
54
|
|
250, 500
|
375
|
66
|
69
|
69
|
56
|
57
|
65
|
- *Responders were patients who achieved at least the minimal clinically important difference (MCID; one and four units for TDI and ΔSGRQ, respectively); TDI, Transition Dyspnoea Index; ΔSGRQ, change from baseline in St George's Respiratory Questionnaire; ΔFEV1, change from baseline in trough forced expiratory volume in 1 second.
- †For the outcomes, each row contains approximately 20% of the column's indicated n, as in the left half of Table 2
