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Table 2 Summary information for averages of ΔFEV1

From: Correlating changes in lung function with patient outcomes in chronic obstructive pulmonary disease: a pooled analysis

  

Number of observations in intervals defined by ml ranges

Percentiles* of observations

Average of ΔFEV1

n

< -500

-500, -50

-50, 50

50, 150

150, 250

250, 500

> 500

Minimum

5%

25%

50%

75%

95%

Maximum

Week 4-12

3313

24

623

695

717

563

554

137

-1180

-198

-20

94

220

466

1966

Week 4-24/26

2389

16

478

476

550

388

377

104

-1148

-203

-30

88

214

474

1782

Week 4-52

1169

6

292

218

273

165

168

47

-755

-223

-52

75

201

464

1607

On treatment

3313

24

708

662

751

536

501

131

-1180

-213

-32

82

208

467

1966

  1. *For example, when averaging over time on treatment, the minimum average ΔFEV1 was -1180 ml and the maximum was 1966 ml; between these points, 5% observations were less than or equal to -213 ml and half were less than or equal to 82 ml; ΔFEV1, change from baseline in trough forced expiratory volume in 1 second.