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Table 2 Summary information for averages of ΔFEV1

From: Correlating changes in lung function with patient outcomes in chronic obstructive pulmonary disease: a pooled analysis

   Number of observations in intervals defined by ml ranges Percentiles* of observations
Average of ΔFEV1 n < -500 -500, -50 -50, 50 50, 150 150, 250 250, 500 > 500 Minimum 5% 25% 50% 75% 95% Maximum
Week 4-12 3313 24 623 695 717 563 554 137 -1180 -198 -20 94 220 466 1966
Week 4-24/26 2389 16 478 476 550 388 377 104 -1148 -203 -30 88 214 474 1782
Week 4-52 1169 6 292 218 273 165 168 47 -755 -223 -52 75 201 464 1607
On treatment 3313 24 708 662 751 536 501 131 -1180 -213 -32 82 208 467 1966
  1. *For example, when averaging over time on treatment, the minimum average ΔFEV1 was -1180 ml and the maximum was 1966 ml; between these points, 5% observations were less than or equal to -213 ml and half were less than or equal to 82 ml; ΔFEV1, change from baseline in trough forced expiratory volume in 1 second.