Nicotinic acetylcholine receptor variants associated with susceptibility to chronic obstructive pulmonary disease: a meta-analysis

Table 5 Association between rs1051730 genotypes and emphysema

Genotype	Number of subjects		Overall effect			Heterogeneity
	COPD	Total	OR (95%CI)	Z	p	Chi²	p	I² (%)
A-allele/G-allele	379/557	728/1288	1.39 (1.16-1.68)	3.48	0.0005	0.01	0.94	0
GA/GG	219/169	452/418	1.37 (1.04- 1.80)	2.25	0.02	1.91	0.17	48
AA/GG	80/169	138/418	1.93 (1.29- 2.90)	3.18	0.001	0.28	0.60	0

ISSN: 1465-993X