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Table 3 Association between rs1051730 A-allele and COPD

From: Nicotinic acetylcholine receptor variants associated with susceptibility to chronic obstructive pulmonary disease: a meta-analysis

  Control COPD OR (95%CI) Z p Chi2 p I2 (%)
Smoking amount Number of subjects A-allele vs G-allele effect Heterogeneity
comparable 479 636 1.29 (1.07- 1.55) 2.62 0.009 1.34 0.25 25
incomparable 2105 2177 1.35 (1.22- 1.48) 6.12 <10-5 0.77 0.86 0
  1. Subgroup analysis was performed according to the comparability of smoking amount between COPD and control group of included studies. Abbreviations: COPD, chronic obstructive pulmonary disease; CI, confidence interval.