Nicotinic acetylcholine receptor variants associated with susceptibility to chronic obstructive pulmonary disease: a meta-analysis

Table 3 Association between rs1051730 A-allele and COPD

	Control	COPD	OR (95%CI)	Z	p	Chi²	p	I² (%)
Smoking amount	Number of subjects		A-allele vs G-allele effect			Heterogeneity
comparable	479	636	1.29 (1.07- 1.55)	2.62	0.009	1.34	0.25	25
incomparable	2105	2177	1.35 (1.22- 1.48)	6.12	<10^-5	0.77	0.86	0

Subgroup analysis was performed according to the comparability of smoking amount between COPD and control group of included studies. Abbreviations: COPD, chronic obstructive pulmonary disease; CI, confidence interval.

ISSN: 1465-993X