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Table 2 Comparison of IL-1β,IL-6, TNF-αand OPG/RANK/RANKL levels among three groups

From: Disturbance of the OPG/RANK/RANKL pathway and systemic inflammation in COPD patients with emphysema and osteoporosis

Variables normal control (n = 20) COPD with normal BMD (n = 30) COPD with low BMD (n = 30)
IL-1β (fg/ml) 122.21 ± 35.14 186.83 ± 104.87† 192.94 ± 115.82†
IL-6(fg/ml) 354.37 ± 83.14 421.52 ± 125.78† 483.73 ± 110.38†‡
TNF-α (fg/ml) 193.09 ± 81.20 261.28 ± 96.09† 324.37 ± 141.29†‡
OPG(pg/ml) 236.50 ± 38.76 240.43 ± 65.77 257.97 ± 86.80
RANK(pg/ml) 82.28 ± 29.76 73.90 ± 50.41 2.24 ± 0.80 †‡
  1. Data are mean (SD) unless otherwise stated.
  2. †p < 0.05 compared with the normal control group.
  3. ‡p < 0.05 compared with the COPD with normal BMD group
  4. COPD: chronic obstructive pulmonary disease, BMD: bone mineral density, IL: interleukin, TNF-α:tumor necrosis factor α, OPG: osteoprotegerin, RANK: receptor activator of NF-κB, RANKL: RANK ligand