Table 1 Demographic, baseline and exercise characteristics of COPD patients
All Patients (n = 48) | Patients with EELV ≥ 75% TLC (n = 23) | Patients with EELV < 75% TLC (n = 25) | |||||
|---|---|---|---|---|---|---|---|
Mean ± SD | Range | Mean ± SD | Range | Mean ± SD | Range | p* | |
Age (yr) | 68 ± 8 | 39-81 | 70 ± 7 | 57-81 | 67 ± 10 | 39-81 | 0.263 |
Females/Males | 16/32 | -- | 7/16 | -- | 9/16 | -- | 0.894 |
BMI (kg/m2) | 26 ± 4 | 19-36 | 26 ± 4 | 20-34 | 26 ± 4 | 19-36 | 0.889 |
VC (% pred) | 84 ± 16 | 55-124 | 81 ± 14 | 55-100 | 87 ± 18 | 60-124 | 0.199 |
FEV1 (% pred) | 55 ± 13 | 33-81 | 47 ± 10 | 33-65 | 62 ± 12 | 34-81 | 0.001 |
TLC (% pred) | 118 ± 20 | 80-177 | 127 ± 19 | 88-177 | 111 ± 17 | 80-139 | 0.004 |
TLco (% pred) | 68 ± 17 | 38-105 | 65 ± 19 | 38-105 | 72 ± 15 | 39-99 | 0.137 |
FEV1/VC (%) | 51 ± 12 | 29-68 | 46 ± 12 | 29-67 | 56 ± 9 | 36-68 | 0.003 |
FEF50/FIF50 ratio (L/s) | 0.41 ± 0.22 | 0.09-0.94 | 0.31 ± 0.18 | 0.09-0.88 | 0.49 ± 0.21 | 0.22-0.94 | 0.003 |
IC/TLC ratio (L) | 0.33 ± 0.10 | 0.19-0.63 | 0.26 ± 0.04 | 0.19-0.36 | 0.40 ± 0.09 | 0.24-0.63 | 0.001 |
HR rest | 81 ± 16 | 47-114 | 83 ± 17 | 52-114 | 80 ± 16 | 47-108 | 0.486 |
HR peak | 118 ± 18 | 71-150 | 115 ± 21 | 71-147 | 121 ± 16 | 93-150 | 0.299 |
Sp O2 rest | 95.6 ± 1.4 | 93-98 | 95.3 ± 1.5 | 93 - 98 | 95.8 ± 1.2 | 93 - 98 | 0.177 |
Sp O2 peak | 94.9 ± 2.1 | 89-98 | 93.8 ± 2.3 | 89 - 98 | 95.8 ± 1.2 | 94 - 98 | 0.0004 |
Peak VO2 (mL/kg/min) | 15.3 ± 3.2 | 10.6-22.5 | 14.1 ± 3.1 | 10.6-22.5 | 16.4 ± 2.9 | 11.5-21.0 | 0.012 |
Peak workload (watts) | 75 ± 24 | 33-128 | 64 ± 22 | 33-106 | 85 ± 21 | 47-128 | 0.001 |
VAS/MW (mm/watts) | 1.25 ± 0.5 | 0.51-2.94 | 1.07 ± 0.3 | 0.63-1.76 | 1.44 ± 0.56 | 0.51-2.94 | 0.006 |
ΔO2Pulse (mL/bpm) | 9.63 ± 2.68 | 5.0-15.0 | 8.65 ± 2.21 | 5.0-15.0 | 10.52 ± 2.80 | 6.0-15.0 | 0.014 |
DP reserve (mm Hg · bpm) | 10,431 ± 4,165 | 1,460-20,560 | 8,509 ± 3,537 | 1,460-16,740 | 12,074 ± 3,862 | 4,360-20,560 | 0.017 |