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Figure 4 | Respiratory Research

Figure 4

From: Cigarette smoke increases TLR4 and TLR9 expression and induces cytokine production from CD8+T cells in chronic obstructive pulmonary disease

Figure 4

Quantitative analysis of the number of CD8+ T cells expressing TLR4 or TLR9 in endobronchial biopsies. The absolute numbers of the singled-stained CD8+ T cells were counted and compared to the absolute numbers of CD8+ T cells expressing TLR4 or TLR9 from COPD patients (n = 6) and healthy controls (n = 5). The percentage of CD8+ T cells expressing TLR4 (A) was significantly higher in COPD patients (92.76 ± 1.18) compared to control subjects (14.38 ± 2.00). The percentage of CD8+ T cells expressing TLR9 (B) was also significantly increased in COPD patients (86.88 ± 0.51) compared to healthy controls (17.97 ± 3.74). Data are represented as mean ± SEM. *** indicate p-values < 0.0001.

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