Table 5 Variability of selected biomarkers in stable subjects.
From: COPD association and repeatability of blood biomarkers in the ECLIPSE cohort
Biomarker | COPD Subjects* | Smoker Controls | Non-smoker Controls | All Subjects |
|---|---|---|---|---|
CC-16 | 132/146 (90%) | 29/35 (83%) | 31/34 (91%) | 192/215 (89%) |
C-reactive protein | 32/153 (21%) | 7/36 (19%) | 12/35 (34%) | 51/224 (23%) |
CCL24 | 51/144 (35%) | 8/32 (25%) | 16/35 (46%) | 75/211 (36%) |
Fibrinogen | 139/156 (89%) | 31/36 (86%) | 35/36 (97%) | 205/228 (90%) |
Hepatocyte growth factor | 57/152 (38%) | 17/36 (47%) | 19/36 (53%) | 93/224 (42%) |
Interleukin-6 | 55/147 (37%) | 22/34 (65%) | 24/36 (67%) | 101/217 (47%) |
Interleukin-8 | 67/141 (48%) | 12/35 (34%) | 13/33 (39%) | 92/209 (44%) |
Interleukin 12p40 | 64/124 (52%) | 14/27 (52%) | 20/30 (67%) | 98/181 (54%) |
CXCL10 | 86/152 (57%) | 19/35 (54%) | 23/34 (68%) | 128/221 (58%) |
CCL2 | 72/154 (47%) | 22/36 (61%) | 13/36 (36%) | 107/226 (47%) |
Matrix metalloproteinase-9 | 53/154 (34%) | 8/36 (22%) | 18/36 (50%) | 79/226 (35%) |
CCL23 | 93/154 (60%) | 20/36 (56%) | 23/36 (64%) | 136/226 (60%) |
Myeloperoxidase | 52/154 (34%) | 7/35 (20%) | 15/36 (42%) | 74/225 (33%) |
CCL-18 | 53/135 (39%) | 15/26 (58%) | 15/35 (43%) | 83/196 (42%) |
Prolactin | 47/148 (32%) | 7/36 (19%) | 9/35 (26%) | 63/219 (29%) |
Surfactant Protein D | 107/145 (74%) | 26/35 (74%) | 30/34 (88%) | 163/214 (76%) |