Table 1 Baseline characteristics of the biomarker cohort.
From: COPD association and repeatability of blood biomarkers in the ECLIPSE cohort
Characteristic | COPD Subjects | Smoker Controls | Non-smoker Controls | |
|---|---|---|---|---|
Number | 201 | 37 | 37 | |
Age (yrs) | 64.5 (6.0) | 60.7 (7.6) | 60.0 (8.8) | |
Male (%) | 73% | 68% | 38% | |
Smoking, pack-years | 45.7 (26.9) | 29.3 (16.5) | 0.0 (0.2) | |
FEV1 % predicted | 43.8 (17.2) | 109.6 (12.3) | 115.9 (11.9) | |
% Low attenuation area on CT (< -950HU) | 22.7 (13.7) | 4.6 (4.5) | 5.3 (5.5) | |
Radiologist Score | < 5% emphysema | 20% | 95% | 97% |
| Â | 5-25% emphysema | 18% | 5% | 0 |
| Â | 25-50% emphysema | 15% | 0 | 3% |
| Â | > 50% emphysema | 48% | 0 | 0 |
% reversibility FEV1 | 9.6 (11.2) | 3.7 (5.1) | 2.2 (4.9) | |
BMI | 26.9 (5.5) | 29.2 (4.9) | 27.1 (6.1) | |
Fat free mass index | 17.1 (2.6) | 18.2 (2.5) | 16.8 (2.6) | |
Number of exacerbations in year prior to enrollment in ECLIPSE | 0 | 46% | 100% | 97% |
| Â | 1 | 26% | 0 | 3% |
| Â | 2 | 18% | 0 | 0 |
| Â | 3 or more | 10% | 0 | 0 |
6 min walk (m) | 384 (124) | Â | Â | |
BODE Index | 3.4 (2.2) | Â | Â | |
mMRC score | 1.9 (1.1) | 0.2 (0.5) | 0.1 (0.4) | |
CES-D score | 11.5 (9.0) | 7.1 (8.8) | 5.3 (5.1) | |
FACIT score | 34.8 (10.6) | 44.4 (8.4) | 47.4 (4.3) | |
SGRQ-C Total score | 52.9 (18.9) | 8.4 (11.9) | 2.5 (2.3) | |